Y CHROMOSOMAL STR LOCUS DYS385 IN
AZOOSPERMIC AND FERTILE MEN FROM THE
AEGEAN REGION OF TURKEY:
IS THERE ANY FORENSIC RELEVANCE?
Unuvar D1, Baransel Isir A2, Cankus G3, Pehlivan S3,*
*Corresponding Author: Associate Professor Sacide Pehlivan, Department of Medical Biology
and Genetics, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey; Tel./Fax: +90-34-
2360-6028; e-mail: spehlivan@ gantep.edu.tr; aybaransel@yahoo.com
page: 39
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Abstract
The DYS385 locus, consisting of two linked short tandem repeat (STR) subloci, is the polymorphic marker on the Y chromosome. The distribution of DYS385 genotypes was studied in 51 fertile and 49 azoospermic male individuals from the Aegean Region of Turkey. Genotype 14-17 was the most frequently observed genotype, and the gene diversity value of the Aegean population (n = 100) was 0.946 in this study. Results of the analyses show that there is a statistically significant difference between azoospermic and fertile males in terms of the DYS385 polymorphism. In addition, the results demonstrate that the DYS385 locus is very useful for human identification in forensic cases and paternity tests in the Aegean Region of Turkey.
Key words: Aegean Region; DYS385 polymorphism; Forensic genetics; Genotypes; Short tandem repeat (STR); Turkey
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1 Ege University, Faculty of Science, Department of Biology, Bornova-Izmir-Turkey
2 Gaziantep University, Faculty of Medicine, Department of Forensic Medicine, Sahinbey-Gaziantep-Turkey
3 Gaziantep University, Faculty of Medicine, Department of Medical Biology and Genetics, Sahinbey-Gaziantep-Turkey
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