HANSOH PHARMA PRESENTED DATA FROM TWO CLINICALSTUDIES OF HS-10382, A NOVEL BCR..ABL1 ALLOSTERIC INHIBITOR, IN CHRONIC MYELOID LEUKEMIA (CML) ... It potently inhibits the phosphorylation of ABL1 and its ...
Terns' lead candidate TERN-701 is an investigational oral allosteric BCR..ABL1 tyrosine ... "The first approval of a BCR..ABL1 tyrosine kinase inhibitor 25 years ago transformed the prognosis for many patients with chronic myeloid leukemia.