A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to ...

Most cell types have an appendage that appears to act as a kind of signaling hub; called a cilium, it's capable of detecting and sending chemical messages. Some specialized cells don’t only carry one ...

The primary cilia observed in this study originated from both animal and human beta cells. The researchers investigated how the skeletal structure (axoneme) formed from microtubules is organized.

The researchers were surprised to find that the genetically engineered mice had the same number of cilia on cells as the mice with deuterosomes, ruling out the central role of deuterosomes in ...

But that wasn’t really the case. Not only do mammalian cells have potential to exhibit de novo generation of cilia—someone predicted this in 1968.

Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia. Nature Biomedical Engineering, 2022; 6 (4): 463 DOI: 10.1038/s41551-022-00880-8 ...

Single-celled algae and animal sperm cells are widely separated in evolution but both swim in the same way, by waving their protruding hairs, called cilia or flagella. Motion is driven by ...

Ex vivo studies have also shown that when cilia become immobile (a state called ciliostasis), viral replication of pathogens like H3N2 influenza increases significantly. Similarly, SARS-CoV-2, the ...

But he is unimpressed that the human cell clusters can “swim” with their cilia. That, he says, is pretty much inevitable if you have beating cilia once the spheroids are freed from the gel matrix.