One of the main factors determining therapeutic antibodies’ half-life is the interaction between the antibody’s Fc region and ...

The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III. Scientific Reports, 2019; 9 (1) DOI: 10.1038/s41598-019-48323-w ...

More information: Patricia S. Grace et al. Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction., Immunity (2025).

(I) Comparison of architecture and antibody binding footprint of HSV-1, HCMV, and EBV post-fusion gB in complex with its DII-specific antibody. The VH and VL of D48, SM5-1, and 3A3 were colored ...

In one, Adam Silverman, Joy Zuchero, and colleagues at Denali in South San Francisco detailed the vehicle’s development, and showed that brain Aβ plummeted when animals were injected with the ...

Notably, switching from Fab to Fv-clasp format markedly enhanced the antibody-assisted crystallization of two biologically important proteins, the extracellular domains integrin α6β1 and sorLA.

Elpiscience Announces CDE IND Clearance of ES014, a First in Class Anti-CD39xTGF-β Bispecific Antibody for Patients with Advanced Solid Tumors December 22, 2022 07:35 PM Eastern Standard Time ...