All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

Researchers identify a stress-responsive RNA fragment in kidney cells that may serve as a biomarker and open new avenues for ...

Guoping Li, Ph.D., of the Department of Anesthesia, Critical Care & Pain Medicine at Massachusetts General Hospital, is the ...

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

Biogenesis and classification of tsRNAs. tsRNA is divided into two types: tRFs and tiRNAs. The widespread presence and high conservation of tsRNAs in digestive tract diseases underscore their ...

Chung-Ang University researchers unveil the biogenesis and role of transfer RNA fragments in cancer progression Study reveals that 5’-tRNAGly (GCC) is a key regulator of gene expression and a ...

The researchers of this study utilized a cryo-EM reconstruction to show how TSEN interacts with pre-tRNA, which has an L-shaped structure, to excise an intron from the long portion of the L. “First, ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction ...

He and his colleagues demonstrated as much in 2019, 1 showing that sup-tRNA readthrough of natural stop codons was minimal compared to that of premature stop codons, likely due to extra termination ...