By deciphering the molecular pathways linking ribosome biogenesis and liver pathology, researchers aim to develop targeted, effective treatments for chronic liver diseases and liver cancer.

This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression. As the center of protein synthesis, ribosomes influence liver regeneration ...

In eukaryotic cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: fibrillar center (FC), dense fibrillar component (DFC), periphery of DFC ...

Advances such as triple agonists, gene editing, and microbiome therapy offer hope for metabolic diseases, but global access ...

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy ...

Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells—a process called ...

The molecular rules underlying autophagy of mitochondria, or mitophagy, provide therapeutic applications for neurodegeerative disease.

Congenital diarrhea and enteropathies (CODEs) are a group of rare disorders that primarily affect the function of intestinal epithelial cells, leading to infantile-onset diarrhea and poor growth ...

A team led by Prof. CHEN Lingling from the Center for Excellence in Molecular Cell Science of the Chinese Academy of Sciences revealed a spatiotemporal separation in the processing of distinct rRNA ...