This work details the cyclic peptide drugs authorized for clinic use between 2001 and 2021 and reveals their future development trends. Romidepsin; Romidepsin is a natural dicyclic peptide discovered ...

Circular and knotted peptides and proteins seem to be, well, coming full circle. Bioactive cyclic peptides have been known for some time. They include compounds like the antibiotic gramicidin S ...