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A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.
As the first crystal structure of this type, the researchers say it will also be useful as a model for other targets in the genome, besides the insulin gene, which form this shape of DNA.
A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein ...
Animation of DNA's knot-like i-motif structure the team mapped in 50,000 locations in the human genome, concentrated in key functional areas including regions that control gene activity.
AlphaFold 3, the latest version of the AI that Google DeepMind detailed today, can also predict the structure of DNA, RNA, ligands and other biological building blocks.
The skin provided the first ever look at the 3-D structure of the extinct animal’s DNA. After years of partial success and failure, the team got access to skin from the head of a woolly mammoth ...