The antimalarial drugs CQ and PPQ work by entering the parasite's digestive vacuole (a compartment resembling a stomach) and altering it so that the parasite poisons itself on its own toxic waste ...

Without this lipid-protein boost, the team found that heat can make the food vacuole start to leak, unleashing its acidic contents into the gel-like fluid that fills the cell and possibly even ...

The protein produced by the pfcrt gene is located in this digestive vacuole and may act as its gatekeeper. In chloroquine-resistant malaria, mutations in pfcrt may encourage chloroquine to "leak ...

New high-resolution images show how malaria parasites evade frontline drugs Date: November 27, 2019 Source: Columbia University Irving Medical Center Summary: The first-ever detailed images of a ...

This complex accumulates at the membrane of the digestive vacuole, as observed by bromine X-ray fluorescence signal, and possibly spreads to other membranes.” ...

Aggregates of ferritin were found in vacuoles, some of which could be identified as food vacuoles. The findings, which provide evidence for a rapid penetration of large molecules into the nucleus, the ...