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As a proof-of-concept, they then used this model to show how the hormone-dependent behaviors of the endometrial epithelium in co-culture with stroma are different from those in monoculture.
In a recent study published in Nature Communications, Simón and his research team analyzed patient cells and patient-derived endometrial organoids to decode an Asherman syndrome-specific endometrial ...
Initial cultures of epithelial and stromal endometrial cells from human donors in the hydrogel remained intact for 15 days, outperforming those grown in Matrigel, which had begun disintegrating by the ...
The schematic illustration of their proposed clonal selection and diversification in normal endometrial epithelium is shown in Figure 1, where each color represents an expanding clone.
After obtaining the endometrial samples, they purified single-cell suspensions of epithelial and stromal cells that were cultured in very low amounts. They found that a small number of these cells ...
Cite this: Use of Docetaxel After Paclitaxel Hypersensitivity Reaction in Epithelial Ovarian and Endometrial Cancer - Medscape - May 01, 2009.
Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk. Med, 2023; 4 (8): 554 DOI: 10.1016/j.medj.2023.07.004 ...
Scientists in the U.K. have succeeded in deriving endometrial organoids using cells extracted from menstrual blood, opening the way to more relevant high-throughput screens for drug discovery and to ...
An endometrial biopsy is a procedure to help diagnose the cause of abnormal bleeding. Learn more here.
Endometrial carcinoma is diagnosed in about 58,500 women in the United States per year. It is linked with obesity, excess estrogen, and the Lynch syndrome. Oral contraceptives lower the risk by 30 ...