Saida: Initial dosages of carboplatin and etoposide were AUC4 [area under the curve] and 80 mg/m 2 in PS 2 cohort, and AUC3 and 60 mg/m 2 in PS 3.

Source Reference: Browne C, et al "Impact of an etoposide chemotherapy shortage on patients with extensive-stage small-cell lung cancer: Results of a natural experiment" JCO Oncol Pract 2024; DOI ...

Patients received four courses of chemotherapy with paclitaxel, carboplatin, and etoposide, administered at 3-week intervals. After completing four courses of treatment, patients with objective ...

PURPOSEA shortage of essential intravenous (IV) etoposide lasted from 2018 until 2020 in Ontario, Canada, allowing for a natural experiment in which external factors (IV etoposide availability) ...