Fanconi anemia (FA) is a rare genetic disease, affecting 1 in 160,000 people. The condition leads to gradual bone marrow failure in about 90% of people affected. Bone marrow is the spongy material ...

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into ...

Fanconi syndrome is a rare condition affecting the kidneys. Read on to learn more about the symptoms of Fanconi anemia, what causes it, what treatments may help, and more.

The 'heart' of the Fanconi anemia core complex, composed of FANCB-FANCL-FAAP100 (now FANCX) proteins, allows the rest of the core complex to assemble, and is necessary for downstream DNA repair.

An antibody treatment developed at Stanford Medicine successfully prepared patients for stem cell transplants without toxic ...

Fanconi anemia is a rare inherited condition that can affect the thumbs. Some people with the condition may be born with extra, missing, or misshapen thumbs. While Fanconi anemia does not affect ...

Fanconi anemia (FA) is a rare, inherited disease primarily affecting children. While the outcome for people with FA tends to be poor, researchers predict that newer molecular and gene therapies ...

Rui Wang, Walter F. Lenoir, Chao Wang, Dan Su, Megan McLaughlin, Qianghua Hu, Xi Shen, Yanyan Tian, Naeh Klages-Mundt, Erica Lynn, Richard D. Wood, Junjie Chen, Traver Hart, Lei Li, DNA polymerase ι ...

Blood 1994; 90: 105–110. Google Scholar Gluckman E, Auerbach AD, Horowitz MM et al. Bone marrow transplantation for Fanconi anemia. Blood 1995; 86: 2856–2862. CAS PubMed Google Scholar ...

The ‘heart’ of the Fanconi anemia core complex, composed of FANCB-FANCL-FAAP100 (now FANCX) proteins, allows the rest of the core complex to assemble, and is necessary for downstream DNA ...

New gene linked to severe cases of Fanconi anemia Date: May 9, 2025 Source: Rockefeller University Summary: Mutations in FANCX appear to cause a lethal form of Fanconi anemia, a finding that sheds ...