In 2004, scientists were able to overcome this genetic imprinting issue to produce embryos from the DNA of two female mice, but achieving the same with two male mice has been much more complicated.

Bioethicist Adrian Villalba writes in “ Queering the Genome “: The potential alteration of genomic imprinting opens the door for an oocyte [egg] to exhibit characteristics similar to a sperm ...

Early development of an embryo is solely supported by maternally deposited RNAs and proteins until its own genome is activated through a process called zygotic genome activation (ZGA). Recent work ...

At the genome editing summit, many thorny issues raised by editing of the germline were punted, breezed past, or cut short before real discussion got underway.

In mice, genome activation occurs at the two-cell stage. In human embryos, it occurs later, when the embryo has gone through a couple of rounds of division to form eight cells.

"For example, many hox genes, which determine the body plan and also differentiation during hematopoiesis [the formation of blood cells], are methylated in the mother's genetic contribution and ...

NEW YORK, June 4, 2025 /PRNewswire/ -- With U.S. birthrates plummeting and IVF on the rise, Nucleus Genomics today launched Nucleus Embryo, the first genetic optimization software that lets ...

Thanks to the CRISPR system, a powerful gene editing tool, scientists may soon be able to edit genes to cure diseases. But the ACMG board pointed out some limitations of gene editing technologies such ...

By genetically testing nearly 1,000 embryos, scientists have provided the most-detailed analysis of embryo fate following human in vitro fertilization. Nearly half the embryos studied underwent ...