IBM, an inflammatory myopathy, often afflicts those in their middle age or later years, presenting symptoms like muscle weakening in the quadriceps and finger flexors, as well as dysphagia.

Results of a systematic review and meta-analysis revealed that JIIMs may negatively impact growth and pubertal development.

Large studies are needed to see if targeted therapies work in the different types of IIM. As IIM is rare, this would best be done by many centres working together internationally.

SAN DIEGO — Clinical trials exploring intravenous immunoglobulin and Janus kinase inhibition headline a robust pipeline for idiopathic inflammatory myopathies, according to a speaker at the 2023 ...

Immune-mediated necrotizing myopathies present with symptoms similar to those of other idiopathic inflammatory myopathies, but the muscle biopsy demonstrates necrosis of muscle fibers, as opposed ...

Inflammatory myopathies and autoimmune gluten-related disorders This article by Dr. Gunhild Alvik Nyborg is published in the journal, Recent Advances in Inflammation & Allergy Drug Discovery, 2024 ...

A study has shed new light on the mechanisms behind idiopathic inflammatory myopathies (myositis), a group of systemic autoimmune disorders known for causing severe muscle weakness, fatigue, and ...

The classification criteria for idiopathic inflammatory myopathies include proximal muscle weakness, laboratory abnormalities (e.g., a positive anti–Jo-1 antibody test or elevated blood levels ...

Jackson, MS - New research suggests that mycophenolate mofetil (MMF) can be used in the management of autoimmune inflammatory myopathy. The finding, published in the March 2005 issue of ...

Inflammatory myopathies are systemic diseases which can affect the skin, lung, heart, joint, and gastro-intestinal tract. Given the involvement of necroptosis in inflammatory diseases of various ...

Idiopathic inflammatory myopathies (IIMs) comprise a group of inflammatory disorders in which there is chronic inflammation of skeletal muscle. This is then followed by muscle weakness. One type ...

Neuropathol Appl Neurobiol. 2012;38:632-646. Liang C, Needham M. Necrotizing autoimmune myopathy. Curr Opin Rheumatol. 2011;23:612-619.