The prevailing model suggests that BKPyV expresses a protein called large tumor antigen, or TAg, early during infection. Early expression of TAg was thought to push kidney cells to replicate the ...

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

A recent study published in Nature used advanced cryo-electron microscopy (cryo-EM) to provide unprecedented insights into the process by which the simian virus 40 (SV40) large tumor antigen (LTag ...

The prevailing model suggests that BKPyV expresses a protein called large tumor antigen, or TAg, early during infection. Early expression of TAg was thought to push kidney cells to replicate the ...

Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection. PLOS Pathogens, 2024; 20 (12): e1012663 DOI: 10.1371/journal.ppat.1012663 ...

Using cryo-electron microscopy and deep learning to observe the helicase Simian Virus 40 Large Tumor Antigen interacting with DNA, the laboratories of KAUST Assistant Professor Alfredo De Biasio ...

Using cryo-electron microscopy and deep learning to observe the helicase Simian Virus 40 Large Tumor Antigen interacting with DNA, the laboratories of KAUST Assistant Professor Alfredo De Biasio ...