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A median fin derived from the lateral plate mesoderm and the origin of paired fins. Nature, 2023; DOI: 10.1038/s41586-023-06100-w ...
Here, we present a simple differentiation protocol to derive a premature form of epicardial cells (or pre-epicardial cells, PECs) from the lateral plate mesoderm, followed by stimulation with BMP4, ...
Lateral Plate Mesoderm: A portion of the mesoderm located on the outer side of the embyo, responsible for forming the limb buds, body wall, heart, and blood vessels.
Suzanne L. Ullmann, The Origin and Structure of the Mesoderm and the Formation of the Coelomic Sacs in Tenebrio Molitor L. [Insecta, Coleoptera], Philosophical Transactions of the Royal Society of ...
In developing lizards and snakes, chemical signals from the cloaca reach a variety of hind leg tissues known as the lateral plate mesoderm, first, resulting in paired penises.
In snakes and lizards, the cloaca is located closer to the lateral plate mesoderm, the same tissue that makes the paired limbs, receives the signal. In mammals, the cloaca is closer to the tail bud.
The lateral plate mesoderm is the developmental origin of the heart, blood vessels, kidneys, connective tissue, as well as major parts of limbs.