Long QT syndrome affects the heart’s rhythm. If it is left untreated, the condition can be fatal. Learn more about the symptoms and treatment here.

This surpassed expert-measured QTc intervals in detecting long QT syndrome (F1 score, 0.84 vs 0.22) and sensitivity (0.90 vs 0.36), including in patients with normal or borderline QTc intervals.

More information: Hui Huang et al. Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations, Science Advances (2018). DOI: 10.1126/sciadv.aar2631 ...

Five factors underlie the ongoing overdiagnosis and misdiagnosis of long QT syndrome (LQTS), including temporary QT prolongation following vasovagal syncope, a "pseudo"-positive genetic test ...

Timothy syndrome, a rare autosomal-dominant disorder, is characterized by presence of a heart arrythmia (long QT syndrome), which causes the cardiac muscle to take longer than usual to recharge ...

Patients with congenital or other forms of long QT syndrome. Investigators recommend that these patients should be informed that drinking grapefruit juice in large quantities may impose some risk.

Long QT Syndrome is considered a rare condition. A person may inherit this condition or develop it at some point in their life. What happens is the heart beats in a fast and chaotic rhythm.

Long QT syndrome is caused by mutations in genes that regulate the heart's electrical activity. These mutations can cause the heart to have sudden, irregular heart rhythms, or arrhythmias.

To test DRIVE, the researchers focused on a rare variant in the gene KCNE1 that causes Type 5 Long QT syndrome (LQT5). The KCNE1 gene encodes a protein that modifies potassium currents.

The Food and Drug Administration (FDA) has granted Orphan Drug designation to LQT-1213, a first-in-class serum glucocorticoid regulated kinase 1 (SGK1) inhibitor, for the treatment of long QT ...

PHILADELPHIA — In people with congenital long QT syndrome, vigorous exercise did not raise risk for death or ventricular arrhythmias compared with nonvigorous exercise, according to the results ...