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Plexiform fibromyxoma is a rare primary mesenchymal tumor of the gastrointestinal tract, first reported by Takahashi in 2007 and officially recognized as a subtype of gastric mesenchymal tumor by the ...
Patients with stage III disease treated with a novel six-drug combination showed improved survival compared with the Malignant Mesenchymal Tumor 84 study (MMT 84; 5-year OS, 60% v 42%, respectively).
A study by Tianjin First Central Hospital researchers reveals the miR-451/ETV4/MMP13 signaling axis as a critical regulator of NSCLC progression. Findings show miR-451 suppression activates ETV4-MMP13 ...
This new article publication from Acta Pharmaceutica Sinica B , discusses how a psychological stress-activated NR3C1/NUPR1 axis promotes ovarian tumor metastasis. Ovarian tumor (OT) is the most lethal ...
Dual therapy ± radiation revealed a pronounced downregulation of epithelial-mesenchymal transition (EMT) and hypoxia-related gene sets. Critically, interferon, EMT, and hypoxia-related gene sets were ...
ADCE-D01 is a first-in-class ADC targeting uPARAP conjugated to the Topo-1 inhibitor payload P-1021. uPARAP is a novel endocytic ADC target that is overexpressed in tumors of mesenchymal origin ...