Clene (NASDAQ: CLNN) , together with its subsidiary Clene Nanomedicine Inc., is preparing to initiate neurofilament biomarker analyses for its lead d ...

A finger-prick blood test reliably measures neurofilament light, enabling remote monitoring that could revolutionize ...

MONTREAL — Levels of neurofilament light chain (Nfl) may be a biomarker of chemotherapy-induced peripheral neurotoxicity (PIPN), new research suggests. Investigators found Nfl levels increased ...

Neurofilament light as a translational biomarker from preclinical drug discovery to clinical application. News-Medical, viewed 27 May 2025, https: ...

Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders. Journal of Neurology , 2019; DOI: 10.1007/s00415-019-09567-8 ...

The blood-based measure of neurofilament light chain was associated with the presence of neuronal injury in those with peripheral neuropathy, according to a systematic review and meta-analysis in ...

Increased levels of neurofilament light in plasma samples correlated with a greater risk for ALS, according to findings from an analysis of plasma samples obtained within 5 years of an ALS ...

Neurofilament light chain (NfL) is a key building block in the "wires" of your brain, which are known as axons. These axons help transmit messages, just like wires transmit electricity.

For neurofilament light chain proteins, people age 75 had an average of 25 picograms per milliliter (pg/ml) compared to people age 50 with an average of 10 pg/ml.

In this phase 3 trial, we randomly assigned adults with SOD1 ALS in a 2:1 ratio to receive eight doses of tofersen (100 mg) or placebo over a period of 24 weeks. The primary end point was the ...