Newark, New Castle, USA, May 15, 2023 (GLOBE NEWSWIRE) -- Growth Plus Reports studied and calculated the size of the global market for pyrimidine Analogues in 2022 and expected it to increase at a ...

In this context, Lakshman and Akula have developed a simple and fast method for preparing new pyrimidine nucleoside analogues, a family in which AZT belongs, and for modifying AZT itself. Along with ...

In the 1990s, pyrimidine fluorescent analogues began to emerge, with notable examples including m 5 K of McLaughlin 11 and the pteridines of Hawkins 12 (Fig. 2).

However, it explains only a small part of inter-individual variability in CDA-A. Therefore, CDA-A assessment in serum remains of interest to identify pts with high risk of toxicity or low efficacy ...

Since the development of the first antifungals in the 1950s, four main antifungal classes have been indicated for the treatment of IFIs: polyenes, triazoles, echinocandins and pyrimidine analogues.

Among the pyrimidine analogues cytosine arabinoside (ara-C, cytarabine) is extensively used in the treatment of acute leukemia, while gemcitabine has more recently demonstrated activity in ...

In nucleosides, purine or pyrimidine bases are connected to the C-1 position of the sugar through the nitrogen on the ring, forming various nucleosides and their derivatives. This is a valuable method ...

Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection, David C. Schultz, Robert M. Johnson, Kasirajan Ayyanathan, Jesse Miller, Kanupriya Whig, Brinda ...

Chemical production of pyrimidine nucleosides by a number of primarily Chinese and Indian companies has allowed oligos, incorporating modified uridines and cytosines, to be generated cost ...

Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors. ChemMedChem, 2015; DOI: 10.1002/cmdc.201500447 ...