Student should read about the project, and understand the basic concept of mouse genetics: Punnett's square, two genes distribution, cell- type specific Cre drivers, LoxP sites, Rosa26 locus, knock-in ...

By using a homologous recombination system based on Cre-loxP, the researchers generated the Myh11-Cre(ER) knock-in mouse line. This newly developed mouse line could enable more specific genetic ...