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Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures.
The enzyme then resets to the beginning of the template sequence and starts over. Stone’s group showed that the section of RNA that is tethered to the protein forms a structure known as an RNA stem ...
Analyses of zebrafish meioc mutants revealed that spermatogonial stem cells with low rRNA transcription caused by nucleolar Piwil1 require Meioc to keep Piwil1 in cytoplasm for the upregulation of ...
They found that many of the uridines which subsequently get modified are found at the bottom of a stem-loop structure that resembles the known optimal PUS1 target. To better understand how PUS1 ...
New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego. The advance holds ...
In a landmark study, researchers from Korea University have discovered a surprising answer: the protein WEE1, traditionally known as a cell cycle regulator and tumor suppressor, can paradoxically ...
What makes blood stem cells transform? Regulation of RNA splicing may be an answer Date: March 21, 2023 Source: Lund University Summary: Researchers have determined a novel mechanism linking the ...
RNA as a Link Between Leukemia and Blood Stem Cells. While today Dr. Kharas is fascinated by RNA biology, he didn’t start his career being interested in it.