Cara Therapeutics is developing an oral formulation for pruritus associated with various conditions after FDA-approved intravenous difelikefalin for ESRD patients. Read more here.

Pruritus in patients undergoing dialysis is associated with poorer quality of sleep, decreased energy, and increased prevalence of depression. 2 A diagnosis of CKD-aP negatively affects QOL scores ...

Additionally, because pruritus associated with ALGS greatly impacts caregivers, having a strong support program like Mirum Access Plus to reduce the strain on families is so important.

Improvement in pruritus from baseline to week 48 with LIVMARLI was predictive of six-year EFS and TFS compared to patients with minimal to no improvement in pruritus; 88% vs 57% (p = 0.0046) and ...

At week 6, the mean percent reduction from baseline VAS pruritus scores in the serlopitant 1 mg and 5 mg groups were 41.4% and 42.5%, respectively, as compared with 28.3% in the placebo-treated group.

Despite currently available treatments targeting AD, there continues to be a lack of options targeting the burden of pruritus in AD patients. View source version on businesswire.com: https://www ...

Moderate to severe pruritus remains a chronic problem in patients on maintenance hemodialysis that can reduce overall quality of life, according to recently published data. Investigators led by ...

Mirum has also submitted LIVMARLI for approval in the U.S. in cholestatic pruritus in PFIC patients three months of age and older, and in Europe, in PFIC for patients two months of age and older.