For example, the amino acid valine is encoded by four different codons. It was long thought that the various codons used to encode amino acid were more or less equivalent., and could be swapped out ...

Synonymous mutations, previously known as silent mutations, are an example of non-coding regions in the genome that are increasingly attracting the interest of biologists. Previous studies have shown ...

If a mutation affects this building block, nothing changes in the amino acid sequence and hence in the resulting protein. In the past, this was referred to as "silent" mutations, but now it is ...

In synonymous mutations, the codon still codes the correct amino acid. As such, these mutations are dubbed "silent" and often considered inconsequential to human health.

Silent mutations are known to have other effects. For example, they can change the way that RNA, the molecule that bridges DNA to protein production, is cut and spliced together.

In synonymous mutations, the codon still codes the correct amino acid. As such, these mutations are dubbed “silent” and often considered inconsequential to human health.

Consider a silent mutation that activates an oncogene—say, by removing a sequence in the gene that usually prevents its expression. “I would need to treat that patient exactly as if there was an ...

There are various ways in which apparently 'silent' DNA mutations — those that don't result in a change in the encoded protein — have untoward consequences. A striking example has emerged in a ...

For example, there is a synonymous mutation in the chloride transmembrane cystic fibrosis transmembrane conductance regulator (CFTR) that slows down CFTR production and folding because it interacts ...

Researchers have identified a number of 'silent' mutations in the roughly 30,000 letters of the COVID-19 virus's genetic code that helped it thrive once it made the leap from bats and other ...

It also found that silent mutations in two other parts of the virus genome — Nsp4 and Nsp16 — appear to have given the virus a "biological edge" over other, existing strains of the virus.