The University of Sydney researchers created a mouse model that mimics this copper-deficient ... their brains already showed buildup of misfolded SOD1, especially in the substantia nigra, followed by ...

Parkinson's is a progressive neurodegenerative disease that is currently incurable. It is typically only diagnosed once ...

The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

Macosko’s team looked at cells from the substantia nigra of eight people who didn’t have Parkinson’s and had agreed to donate their brains for research after death. The researchers used a ...