With Down Syndrome, a person's cells contain a third copy of chromosome 21 -- hence the disorder's scientific name, trisomy 21. Kanako was born in captivity in 1992 at a Japanese wildlife facility.

The new doll, part of Mattel’s 2023 Fashionistas slate, has a number of physical attributes that are associated with Trisomy 21, such as a rounder face, smaller ears, a flatter nasal bridge and ...