Although amino acids are often shown in textbooks as the right-hand structure, they actually mostly exist as the left-hand structure. The simplest, and smallest, amino acid is glycine for which the ...

Our structure of the CASTOR1-arginine complex reveals that a nicely tailored pocket on CASTOR1 is employed to recognize arginine, but not other common amino acids such as lysine and leucine ...

However, the mechanism by which the mTORC1 pathway detects and transmits this arginine signal has been elusive. Here, we present the 1.8 Å crystal structure of arginine-bound CASTOR1.

Amino acids are organic compounds that serve as the fundamental building blocks of proteins. They play a crucial role in the structure, function, and regulation of the body's tissues and organs. Amino ...

New deep-learning approach predicts protein structure from amino acid sequence Date: April 17, 2019 Source: Harvard Medical School Summary: A scientist has used a form of artificial intelligence ...

These polypeptide chains of amino acids can be shaped as helixes or sheets, which come together to form a 3D structure. The 3D structure of proteins is referred to as its “tertiary structure”.

Cryo-EM structure of the human neutral amino acid transporter ASCT2. Nature Structural & Molecular Biology, 2018; 25 (6): 515 DOI: 10.1038/s41594-018-0076-y ...