Congenital hypertrophy of the retinal pigment epithelium is a typically benign, asymptomatic, pigmented fundus lesion. A congenital hamartoma of the retinal pigment epithelium (RPE), …

Clarify the differences between Familial Adenomatous Polyposis (FAP)-associated Congenital Hypertrophy of the Retinal Epithelium (CHRPE) and benign variants with regards to lesion …

CHRPE is a flat, darkly pigmented spot found in the back of your eye. It can vary in size, ranging from a few to more than 10 mm in diameter. They are composed of enlarged cells with densely …

Nov 28, 2014 · My 14-year-old son has worn glasses for nearsightedness since he was 8 years old. At his regular exam, the optician examining his eyes told me he has a CHRPE (congenital …

Learn more about Congenital Hypertrophy of the RPE (CHRPE).

Dec 15, 2024 · CHRPEs can be idiopathic or be associated with Gardner’s syndrome, a variant of familial adenomatous polyposis (FAP). “The goal is to recognize the unique presentation of …

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a harmless, pigmented fundus lesion that can be of various forms: solitary, grouped, and atypical, [1] and are found …

CHRPE has been reported in the absence of colonic polyposis but has been reported in up to 90% of patients with some variant of FAP and is a highly sensitive marker.

Oct 16, 2015 · Congenital hypertrophy of the retinal pigment epithelium (CHRPE) may simulate choroidal melanoma in certain cases. We report unique clinical features we have observed in …

Sep 9, 2009 · CHRPE represents RPE cells that are twice their normal size and contain densely packed, large melanin granules. CHRPE lesions tend to be unilateral in most cases and can …