Open Access Published by De Gruyter

Volume 92 Issue 10

Issue of Journal of Osteopathic Medicine

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Letters to the Editor

Open Access October 1, 1992

Response: Physiologist views osteopathic medicine from different angle

Hadi Hedayati

Page range: 1220A-1220A

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Open Access October 1, 1992

AAO funded Frymann study

John P. Goodridge

Page range: 1220B-1220B

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Open Access October 1, 1992

Response: AAO funded Frymann study

Viola Fryman, M. Faao

Page range: 1220C-1220C

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Open Access October 1, 1992

Physiologist views osteopathic medicine from different angle

Philip B. Hultgreen

Page range: 1215-1215

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Open Access October 1, 1992

Serologic testing only part of Lyme diagnosis

John H. Yost

Page range: 1218-1218

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New and Noteworthy

Open Access October 1, 1992

Medi-notes

Thomas Wesley Allen

Page range: 1227-1227

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CME Quiz Answers

Open Access October 1, 1992

Editorial Comments

Open Access October 1, 1992

News

Open Access October 1, 1992

Editorials

Open Access October 1, 1992

Rising US infant mortality rate requires action

Thomas Wesley Allen

Page range: 1246-1246

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Open Access October 1, 1992

Heed 'Voices From the Future' and reform GME training

Christopher Meyers, T. Mpa

Page range: 1248-1248

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Brief Report

Open Access October 1, 1992

Transplantation in the treatment of paralysis agitans (Parkinson's disease)

Enrico Fazzini,

Page range: 1255-1255

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Abstract

Over the past 3 years, there has been great interest in transplantation therapy in the treatment of Parkinson's disease. Following the impressive results reported by Madrazo in the spring of 1987, more than 350 cases of adrenal medullary implantation have been performed worldwide. There has been a significant reduction in "off" time and an increase in "on" time without chorea in 40% of patients having this procedure. The duration of effect is 1 year in half of these cases, with the other half (20% of all patients) still demonstrating significant improvement 3 years after the procedure. The mechanism of the bilateral beneficial improvement is unknown. The survival of adrenal medullary tissue has not been demonstrated at autopsy. It is thought that the mechanism of improvement involves either regenerative sprouting of the remaining dopamine producing neurons as a consequence of the release of neurotrophic factors or an interruption of the striatal pallidal output inhibitory influence of the basal ganglia on the thalamus (or both). Fetal mesencephalic implantation has also been attempted in more than 100 cases worldwide. The improvements when seen are not any more dramatic than those following the best results of adrenal medullary implantation. Graft survival has not been proved; it remains a possibility that interruption of the putaminosubthalamic pallidal pathway or a trophic influence of the tissue provides an alleviation in parkinsonism. The ethical controversy, need for long-term immunosuppression, and difficulty with obtaining tissue of the appropriate age and delivering the appropriate quantity to the putamen have made this technique less than adequate. Newer techniques employing genetic engineering, cultures of adrenal medullary tissue, and encapsulated xenografts are being investigated.

Clinical Practice

Open Access October 1, 1992

Magnetic resonance imaging of hepatic neoplasms

Mark T. DiMarcangelo

Page range: 1261-1261

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Abstract

Excellent diagnostic images of the liver can now be obtained with magnetic resonance imaging (MRI) because of new imaging techniques. The flow void phenomenon allows excellent anatomic detail of the liver. Morphologic features, comparson of tumor signal to normal parenchymal signal, and tumor behavior in various pulse sequences help to define liver tumors. The MRI characteristics of primary hepatomas, cavernous hemangiomas, hepatic cysts, liver adenomas, and focal nodular hyperplasia are among the hepatic lesions described. In most instances, MRI helps in differential considerations and in some cases will provide a specific diagnosis.

Open Access October 1, 1992

Managing a patient with progressive HIV disease

Page range: 1267-1267

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Abstract

This monthly series was developed from the AOA Task Force on AIDS Writers' Workshop, held August 16 to 18, 1991, in New York. The workshop was sponsored by an education grant from Burroughs Wellcome. It will provide brief clinical updates and perspectives on the human immunodeficiency virus (HIV). Readers may request tear sheets from the AOA editorial offices.

Medical Education

Open Access October 1, 1992

Voices From the Future: What students, interns, and residents want from osteopathic graduate medical training

David Kushner, Joan Cooney

Page range: 1269-1269

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Abstract

The need to attract students to-and keep them in-osteopathic internship and residency programs is great. Recognizing this fact, the osteopathic hospitals, through the American Osteopathic Hospital Association, have placed a renewed focus on liaisons with osteopathic medical education. Voices From the Future represents one such effort. This report reveals how osteopathic medical students, interns, and residents perceive the current state of osteopathic graduate medical education programs as well as the changes that they would like to see incorporated.

Case Report

Open Access October 1, 1992

Guillain-Barre syndrome, pregnancy, and plasmapheresis

E. Ross Clifton

Page range: 1279-1279

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Abstract

The case of Guillain-Barre syndrome (acute inflammatory polyradiculoneuritis) in pregnancy reported here brings the total reported number to 35. The patient had plasmapheresis with no maternal or fetal complications. She did not require mechanical ventilation. This is only the fifth reported case of Guillain-Barre syndrome in the gravid patient involving plasmapheresis. There have been no controlled studies assessing the safety of plasmapheresis in the pregnant patient with the disorder. The possible'risks ofthe procedure need to be weighed against the high maternal mortality rate in such a patient.

Abstracts

Open Access October 1, 1992

Thirty-Sixth Annual AOA Research Conference Abstracts, 1992: Part 2

Page range: 1283-1283

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New and Noteworthy

Open Access October 1, 1992

New Products and Services

Page range: 1296-1296

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CME Quiz

Open Access October 1, 1992

CME Quiz

Page range: 1301-1301

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About this journal

The Journal of Osteopathic Medicine, founded in 1901 and known for 119 years as the Journal of the American Osteopathic Association, is the premier scholarly, peer-reviewed publication of the osteopathic medical profession. The mission of JOM is to serve as an international forum for the dissemination of scientific literature that incorporates an integrative, comprehensive, patient-centered approach to clinical care and improving health. JOM conducts double-blind peer review of academic research manuscripts from a wide variety of medical specialties, covering the full spectrum of clinical settings in which osteopathic physicians practice. All submissions are vetted by a distinguished group of Section Editors led by Editor-in-Chief Ross Zafonte, DO, and supported by a full Editorial Board.

JOM publishes original research, narrative and systematic review articles (including meta-analyses), clinical practice descriptions, and a very limited number of case reports, all of which are described fully in our Instructions for Authors. JOM is particularly interested in original scientific research that provides quantitative analysis of and contributes significantly to the evidence base underpinning current practices in osteopathic medicine, including but not limited to neuromusculoskeletal medicine. We also accept research submissions documenting trends and changes in education for osteopathic medical students. The ultimate focus of all material published in JOM is to support, enhance, and advance patient care through evidence.

Volume 92 Issue 10

Issue of Journal of Osteopathic Medicine

Response: Physiologist views osteopathic medicine from different angle

AAO funded Frymann study

Response: AAO funded Frymann study

Physiologist views osteopathic medicine from different angle

Serologic testing only part of Lyme diagnosis

Medi-notes

CME Quiz Answers - September

Editorial Comments

Federal Update

Rising US infant mortality rate requires action

Heed 'Voices From the Future' and reform GME training

Transplantation in the treatment of paralysis agitans (Parkinson's disease)

Abstract

Magnetic resonance imaging of hepatic neoplasms

Abstract

Managing a patient with progressive HIV disease

Abstract

Voices From the Future: What students, interns, and residents want from osteopathic graduate medical training

Abstract

Guillain-Barre syndrome, pregnancy, and plasmapheresis

Abstract

Thirty-Sixth Annual AOA Research Conference Abstracts, 1992: Part 2

New Products and Services

CME Quiz