Charles Krauthammer wurde am 13 März 1950 in New York City, New York, USA geboren. Er war mit Robyn Trethewey verheiratet. Er starb am 21 Juni 2018 in Atlanta, Georgia, USA.
When he was a medical student, had a diving accident, in Massachusetts in July 1972, which injured his spinal cord and left him paralyzed. Later regained the use of the upper part of his body.