Trivia

Was the original choice for the female lead in Cuatro bodas y un funeral (1994). Prior to leaving for the UK to begin filming, stopped off in Texas to see her mother. As her mother was walking towards Jeanne to greet her, she collapsed and died instantly. As a result, Andie MacDowell stepped in and played the role.

She was originally cast as "Mia Wallace" in Quentin Tarantino's Tiempos violentos (1994), but had to turn down the role. She was replaced by Uma Thurman.

Replaced Robin Wright, due to pregnancy, as Abby McDeere in Sin salida (1993) with Tom Cruise.

Her father, Tom Tripplehorn, was a guitarist with Gary Lewis & The Playboys.

Studied in the Drama Division of The Juilliard School at Lincoln Center in New York City. Was a member of Group 19 (1986-90), which also included Laura Linney.

Has a younger brother who is a drummer/rock musician. He appeared briefly in La dura realidad (1994) as the drummer of Ethan Hawke's band, but was not credited.

Spokesperson for the World Monuments Fund. (2009)

Graduated in 1981 from Edison High School in Tulsa. Spent one semester at the Tulsa University.

Was considered for the role of Dr. Chase Meridian in Batman eternamente (1995).

Nominated as Outstanding Actress in a Made For Television Movie in The Women's Image Network (WIN) Awards 2012 for her work the film FIVE.

On 5/11/02 son August Tripplehorn Orser, born at Cedars-Sinai Medical Center (Los Angeles), 7 lb. 8 oz.

The Pact (2012) is her first appearance, as part of the team, as Agent Alex Blake.