While the original Hataraku Saibou series does make us feel for the characters/cells, this one goes slightly beyond that. If the original version made you feel emotional, this one has the potential to make you drown in guilt. Just like the original series, the red blood cells teach us about the work ethics and that we should always carry on as long as there is life, but in this one they become somewhat complex characters too. The main blood cell of the series would question everything, including his work and himself.
In this version, you would see characters getting more messed up and they keep realizing that it is impossible to escape this hell(or this unhealthy body). Even the platelets won't sound cute anymore.(Yes, they are cute but have a stronger personality now). They just know it has become a serious business now.
This series is a good scolding for anyone living an unhealthy life. At times, it may even sound like a personal attack(lol!). When the red blood cell, in his frustration, starts attacking the body while shouting 'Quit smoking, do exercise etc.', that scene really hit me hard.
The ending, very unusual(especially the post credit scene). It is so weird that it is so good. I expected cells to shout 'Shinzou wo Sasageyo' in the last episode. I really had high Hopes.
While this is a must watch, I feel one should watch the original series first.
