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Rosario spends the night with her grandmother's body while she waits for the ambulance to arrive, during a severe snowfall, Rosario is attacked by otherworldly entities that have taken control of her grandmother's body.

Rosario "Rose" Fuentes, a successful Wall Street stockbroker, receives news of her estranged grandmother Griselda's sudden death. Despite an impending snowstorm, Rosario returns to Griselda's apartment in New York City to sort through her belongings. Upon arrival, she's informed by the building superintendent, Marty, that due to the storm, emergency services are delayed, leaving her to spend the night alone with Griselda's corpse

As the night progresses, Rosario begins to experience unsettling phenomena. She discovers a hidden chamber in the apartment filled with occult artifacts, including a Palo spell book, voodoo-like dolls, a human skull, and animal skeletons. These items reveal Griselda's practice of Palo, a syncretic religion blending African spiritualism and Catholicism.

Rosario learns that Griselda had been performing rituals requiring daily blood sacrifices. Believing that her grandmother attempted to curse her, Rosario attempts to perform a ritual to break the curse, but to no effect. Supernatural occurrences escalate as Rosario is tormented by visions of her deceased mother, Elena, appearing as a decaying corpse.

After a conversation with a neighbor, Joe, Rosario realizes that Griselda has made a deal with the evil spirit Kobayende, to protect Rosario and help her realize her dreams. Rosario manages to perform a ritual that traps Kobayende inside Griselda's corpse.

When morning arrives, Rosario's father comes to the apartment. It is then that Rosario discovers that her father was the one who made the deal with Kobayende and not her Grandmother, and that Griselda was offering her blood to keep Kobayende at bay. Rosario's father attempts to continue the blood sacrifices, but that causes him to become possessed by Kobayende and attack Rosario. The neighbor, Joe, attempts to come to Rosario's help, but Kobayende murders him. Eventually, Rosario manages to kill her father, and believes to have thus defeated Kobayende.

In a final scene, Rosario is seen helping the doorman of her firm's building, who had previously approached her for help but was denied due to his low income. After the doorman and his wife leave, however, Kobayende's decayed hand erupts from Rosario's mouth. Courtesy of Wikipedia.