The name of Gru's alma mater is Lycee Pas Bon. Translating from French to English, the name is No Good High School.
Miranda Cosgrove was 17 when she voiced Margo in the first film. By the time of the fourth film, she was 31 when the movie entered production.
When Gru and his family break into the castle, the plaque on the desk reads Principal Übel Schlecht. This translate literally as "Principal Mega Bad".
Costing $100 million, this is the most expensive film in the franchise. It is also the most expensive Illumination film, tied with Super Mario Bros. le film (2023).