One of the film's writers, David Guion, was on set one day and noticed that Steve Carell was left handed. "I didn't know you were left handed" he remarked to the actor. "I'm not", replied Carell, "but my character is".
The exterior shot of the house where the dinner is held is the same as "stately Wayne Manor" from the original Batman television series.
In one of the mice dioramas, a bottle of Dom Perignon is called "Veber". Francis Veber wrote and directed Le dîner de cons (1998), the film which inspired this remake.