Jenuse started his career as an assistant director in the South Indian film industry. He worked on several ad films during his time at Nirvana Films, headed by Prakash Varma. He then went on to assist his father and many other renowned filmmakers like Lal Jose and Aashiq Abu. In 2015, he debuted as writer and director with 100 Days of Love. The film was a romantic comedy and it was well received not only in Malayalam but also several other languages including in Hindi. In 2019, he directed his second film 9(Nine) which was a science fiction horror film. It was jointly produced by Prithviraj Productions and Sony Pictures.
