Peter Fernandez and Corinne Orr, the original English voices of Speed Racer/Racer X and Trixie/Spritle in Mahha GoGoGo (1967), voice race announcers in the film.
After winning a race, Speed Racer jumps out of his car while it's still moving and strikes a pose. This scene replicates the trademark pose of Speed Racer in the opening credits of Mahha GoGoGo (1967).
Christina Ricci admitted she never watched an episode of the original anime prior to being cast as Trixie.
A working Mach 5 was built for the film, along with several other full size cars, including Racer X's Shooting Star. All driving scenes were filmed with the actors sitting in a gimbal, a race car cockpit with a computer-programmed hydraulic system.
Andrés Cantor: Spanish sports commentator (infamous for his scream of "Gooaaallll!" in soccer matches) appears as a commentator at the Grand Prix.