In 1971, she joined a coalition in New York City that was created to
lobby for reforms within the American Society for Prevention of Cruelty
to Animals (ASPCA). One year later, she was invited to sit on the
ASPCA's Board of Directors, the first woman to serve on the board in
the organization's 106-year history. In 1975, however, Wyler filed a
lawsuit against her fellow board members, charging them with corporate
waste and indifference to animal suffering; as a result, she was the
first person ever to be dropped from the board.