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Aspiring film actress Penny moves into a Pasadena apartment across the hall from brilliant, but socially awkward, physicists Sheldon Cooper and Leonard Hofstadter and shows them how little they know about life outside of the lab.

A 20-something bachelor bartender becomes an unlikely parent when an ex-girlfriend leaves a baby girl on his doorstep.

After a bad break-up, Jess, an offbeat young woman, moves into an apartment loft with three single men. Although they find her behavior very unusual, the men support her - most of the time.

The satiric half-hour adventures of a working-class family in the misfit city of Springfield.

Tessa Altman is used to the big city, but when her dad moves her away, she has to adapt to her new suburban life in Chatswin.

Two young women waitressing at a greasy spoon diner strike up an unlikely friendship in the hopes of launching a successful business - if only they can raise the cash.

F.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.

An invisible and mysterious force field descends upon the small town of Chester's Mill, Maine, USA, trapping residents inside, cut off from the rest of civilization. The trapped townspeople must discover the secrets and purpose of the "dome" or "sphere" and its origins, while coming to learn more than they ever knew about each other and animals too.

Follows the escapades and relationships of a group of neighbors living in Gulfhaven, Florida.

A psychotherapist's private life comes apart at the seams when she discovers that her husband is cheating on her. Dr. Dani Santino throws herself fully into her work and soon becomes the most sought-after therapist for celebrity clients.

Ex-baseball-player Charlie is an anger-management therapist who has small-group sessions at home, an OCD teen daughter, an ex-wife, and a sex-buddy/therapist.

Boston's assertive detective Jane Rizzoli and steady medical examiner Maura Isles are hailing from very different economic backgrounds, but the strong, competent women effectively work together to solve the city's most puzzling crimes.

After a family scandal leaves Mel, a local politician, in charge of her niece and nephew, she hires a man named Joe to become the family's male nanny, or "manny."

Three 30-something dads struggle as parents because they are still children at heart.

Three middle-aged best friends from Los Angeles are flying to Paris when their plane makes an emergency landing in Cleveland. Realizing that all the norms from Los Angeles don't apply anymore, they decide to celebrate a city that values real women and stay where they're still considered hot.

A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.

A group of divorced friends tries to get back to the single life.

Level-headed son Michael Bluth takes over family affairs after his father is imprisoned. But the rest of his spoiled, dysfunctional family are making his job unbearable.

Takes an irreverent look at parenthood through the point of view of an acerbic working mother, along with her stay-at-home husband and opinionated parents.

Two couples and their single friend, all at different stages in their relationships, deal with the complications of dating, commitment, and marriage.

Convicted of a decade-old crime of transporting drug money, ordinarily law-abiding Piper Chapman is sentenced to 18 months behind bars and quickly discovers the realities of life-changing prison time.

Chronicles how cultures collide when a white family and a Latino family are bonded together by their children who fall in love followed quickly by an unplanned pregnancy.