28 wins & 116 nominations
- 2004 Nominee Saturn Award
- Best Supporting Actress
- 2025 Nominee Golden Globe
- Best Performance by a Female Actor in a Television Series - Drama
- 2015 Nominee Golden Globe
- Best Performance by an Actress in a Supporting Role in a Motion Picture
- 2006 Nominee Golden Globe
- Best Performance by an Actress in a Motion Picture - Comedy or Musical
- 2005 Nominee Satellite Award
- Outstanding Actress in a Motion Picture, Comedy or Musical
- 2004 Winner Audience Award
- Best International Actress
- 2003 Winner ALFS Award
- British Newcomer of the Year
Tied with Martin Compston for Sweet Sixteen (2002).
- 2004 Nominee MTV Movie Award
- Breakthrough Female Performance
- 2003 Nominee MTV Movie Award
- Best Trans-Atlantic Breakthrough Performer
- 2015 Winner Ensemble Cast Award"The Imitation Game (2014) is one of the very best ensembles to grace the screen this season. Benedict Cumberbatch and Keira Knightley lead an outstanding cast in The Imitation Game, a film about Alan Turing as he attempts to crack Germany's Enigma machine. The Palm Springs International Film Festival is proud to present the entire cast of The Imitation Game with the Ensemble Performance Award."Shared with: Benedict Cumberbatch · Matthew Goode · Rory Kinnear · Allen Leech · Matthew Beard · Charles Dance · Mark Strong
- 2013 Nominee People's Choice Award
- Favorite Dramatic Movie Actress
- 2009 Nominee People's Choice Award
- Favorite Female Movie Star
- 2008 Winner People's Choice Award
- Favorite Female Action Star
- 2005 Nominee People's Choice Award
- Favorite Female Action Movie Star
- 2014 Nominee SDFCS Award
- Best Ensemble
Shared with: Benedict Cumberbatch · Matthew Goode · Rory Kinnear · Allen Leech · Matthew Beard · Charles Dance · Mark Strong
- 2015 Nominee Actor
- Outstanding Performance by a Cast in a Motion Picture
Shared with: Matthew Beard · Benedict Cumberbatch · Charles Dance · Matthew Goode · Rory Kinnear · Allen Leech · Mark Strong
- 2007 Winner Teen Choice Award
- Choice Movie Actress: Action Adventure
- 2011 Winner Empire Award
- Empire Hero Award
- 2004 Nominee VES Award
- Outstanding Performance by a Male or Female Actor in an Effects Film
- 2002 Winner Golden Wave
- Best Actress (Meilleure Comédienne Long Métrage)
Tied with 'Parminder K. Nagra' for Bend It Like Beckham (2002).
- 2004 Nominee PFCS Award
- Best Ensemble Acting
Shared with: Hugh Grant · Colin Firth · Sienna Guillory · Liam Neeson · Lulu Popplewell · Emma Thompson · Kris Marshall · Heike Makatsch · Martin Freeman · Joanna Page · Chiwetel Ejiofor · Andrew Lincoln · Nina Sosanya · Martine McCutcheon · Laura Linney · Thomas Brodie-Sangster · Alan Rickman · Rodrigo Santoro · Rowan Atkinson · Claudia Schiffer · Bill Nighy · Gregor Fisher · Rory MacGregor · Carla Vasconcelos · Shannon Elizabeth · Denise Richards · Elisha Cuthbert · Lúcia Moniz - 2004 Nominee PFCS Award
- Breakout Performance - On Screen
- 2007 Nominee National Movie Award
- Best Performance by a Female
- 2013 Nominee EDA Special Mention Award
- Best Depiction of Nudity, Sexuality, or Seduction
Shared with: Aaron Taylor-Johnson - 2013 Nominee EDA Special Mention Award
- Most Egregious Age Difference Between the Leading Man and the Love Interest
Steve Carell (age 50) and Keira Knightley (age 27).Shared with: Steve Carell - 2012 Nominee EDA Special Mention Award
- Best Depiction of Nudity, Sexuality, or Seduction
For the scene where Carl Jung (Fassbender) spanks Sabina Speilrein (Knightley).Shared with: Michael Fassbender
- 2003 Winner Golden Schmoes
- Breakthrough Performance of the Year
- 2003 Winner Golden Schmoes
- Best T&A of the Year
- 2003 Nominee Golden Schmoes
- Favorite Celebrity of the Year
- 2008 Nominee Gold Derby Film Award
- Ensemble Cast
Shared with: Brenda Blethyn · Michelle Duncan · Romola Garai · James McAvoy · Vanessa Redgrave · Saoirse Ronan · Juno Temple · Harriet Walter · Julia West
- 2007 Nominee Bravo Otto Germany
- Best Actress (Schauspielerin)
- 2006 Nominee Bravo Otto Germany
- Best Actress (Schauspielerin)
- 2003 Nominee Bravo Otto Germany
- Best Actress (Schauspielerin)
- 2014 Nominee Georges Award
- Best Foreign Actress of the Decade
- 2013 Nominee Georges Award
- Best Foreign Actress of the Year
- 2008 Nominee Georges Award
- Best Foreign Actress
- 2006 Nominee Georges Award
- Best Actress
- 2015 Nominee Palmarés blogos de oro
- Best Supporting Actress (Mejor Actriz de reparto)
- 2025 Nominee CCA Super Award
- Best Actress in an Action Series, Limited Series or Made-for-TV Movie
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