- A good friend of actress Thelma Todd, she was at a dinner given in Todd's honor the night of Todd's mysterious death from carbon monoxide poisoning. Margaret was so distraught that she had to bow out of a picture she was filming Murder by an Aristocrat (1936). Marguerite Churchill was given her assignment.
- Sister-in-law of actor William Hopper.
- Co-starred with Bette Davis when the latter won her two Best Actress Oscars for Dangerous (1935) and Jezebel (1938).
- Her close companion was actress Mary McCarty.
- She has appeared in two films that have been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: Baby Face (1933) and Jezebel (1938).
- Sister of actress Jane Gilbert.
- Frequently cast in movies starring James Cagney during the 1930's.
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