David Letterman, Charles Barkley, Shaquille O'Neal, Ernie Johnson, and Kenny Smith in Charles Barkley (2024)

Milton Davis Jr. and Shaquille O'Neal in Pepsi, Where's My Jet? (2022)

Shaquille O'Neal and Kobe Bryant in Episode #1.6 (2022)

Shaquille O'Neal, Asante Jones, and Kelli Dawn Hancock in Ballerz (2011)

Larry Flash Jenkins, Mykel Shannon Jenkins, Shaquille O'Neal, Asante Jones, Indira G. Wilson, and Lawrence Adimora in Ballerz (2011)

Shaquille O'Neal in Rich & Shameless (2022)

Shaquille O'Neal, Stephen Jackson, and Matt Barnes in The Best of All the Smoke with Matt Barnes and Stephen Jackson (2020)

Francis Capra and Shaquille O'Neal in Kazaam (1996)

Bernie Mac and Shaquille O'Neal in The Bernie Mac Show (2001)

Victoria Beckham and Shaquille O'Neal in The Late Late Show with James Corden (2015)

Reggie Miller, Shaquille O'Neal, Chris Webber, Nate Robinson, and Kyrie Irving in Uncle Drew (2018)

Lisa Leslie, Reggie Miller, Shaquille O'Neal, Chris Webber, Erica Ash, Lil Rel Howery, Nate Robinson, and Kyrie Irving in Uncle Drew (2018)

Shaquille O'Neal in Late Night with Seth Meyers (2014)

Flea, Shaquille O'Neal, and Lewis Pullman in Highston (2015)

Nick Nolte and Shaquille O'Neal in Blue Chips (1994)