- Says her favorite genre is the Musical.
- Youngest actor ever to have attended NY's Actors Studio, when she was 17.
- Replaced Carrie Fisher for the role of Miss Scarlet in Clue (1985).
- Portrayed Lois Lane in the made-for-TV musical It's a Bird... It's a Plane... It's Superman! (1975) and tried out for the same role in Superman (1978), but lost to Margot Kidder. Her screen test was later included as a DVD extra.
- Was extremely upset at first about her performance as the gangster's moll in Victor/Victoria (1982) prior to its release, having thought she went horribly over the top. She did go over the top and the audiences loved her for it. Lesley was nominated for a "Supporting Actress" Academy Award, her only nod so far.
- Was originally offered Jean Seberg's role in Paint Your Wagon (1969).
- Suffered from anorexia nervosa in her teen years and into her twenties.
- Was supposed to play the role of Brenda in Goodbye, Columbus (1969), but she got pregnant and had to be replaced. Ali MacGraw then got the part.
- Starred in an early 1970s busted TV pilot as "Cat Ballou," the role Jane Fonda made famous on film.
- Auditioned for the role of Liesl in The Sound of Music (1965).
- Walt Disney hand-picked Lesley for the ingénue role in the film The Happiest Millionaire (1967) after her "Cinderella" success. This film was the last live-action movie Disney supervised before his death.
- Was fired after only the second day of filming for The Devil You Know (2013) due to reported unreasonable 'diva' demands and tantrums. Similar reports were made back in 1997 when Warren wasn't getting star treatment for her Broadway show: 'Dream: the Johnny Mercer Musical Revue'.
- Of all her television experiences, Warren said she had an especially great time on Will & Grace (1998) and Dr. Kildare (1961), and that her favorite television experience was the making of Cinderella (1965).
- Turned down a chance to audition for the Kathleen Turner role in Romancing the Stone (1984).
- Acting protégée of Peter Graves.
- Was very proud of her work in Willing to Kill: The Texas Cheerleader Story (1992), and was disappointed that it got clobbered by an HBO movie on the same story (The Positively True Adventures of the Alleged Texas Cheerleader-Murdering Mom (1993)) that came out at about the same time, starring Holly Hunter.
- She has a son, Christopher Peters, from producer Jon Peters.
- Started working on her first Broadway show (110 in the Shade) at sixteen and a half years old.
- Warren says she won the highly-coveted part of Susan's high-maintenance mom "Sophie" on Desperate Housewives (2004) because of her son, Christopher Peters.
- Dated Scott Baio, Robert Blake, Bobby Darin, Robert Evans, Val Kilmer, David Sanborn, Paul Stanley and John Strasberg. She had a long-term boyfriend in the latter part of the 1980s but refused to identify him.
- Offered the stage role of Norma Cassidy (her Oscar-nominated role) in the stage version of "Victor/Victoria" starring Julie Andrews, but had to turn it down due to other movie commitments.
- Played Lois Lane in a television production of the musical It's a Bird... It's a Plane... It's Superman! (1975), and later screen tested for the role in Superman (1978).
- Was student at School of American Ballet when she switched to acting.
- Had to turn down Mary Steenburgen's role in Step Brothers (2008) because of scheduling conflicts with In Plain Sight (2008).
- At age 13, she won a scholarship to study with ballet legend George Balanchine.
- When she first auditioned for Cinderella, she was so nervous that the audition tanked. She had to audition a second time, and then was hired.
- Won the most promising newcomer on Broadway for her work in 110 in the Shade in 1963.
- Her father was a World War II vet and realtor while her mother was a nightclub singer who stopped working when Lesley Ann was born.
- Appeared as one of the celebrity models in a charity fashion show staged by Thierry Mugler to benefit AIDS Project Los Angeles. (April 1992)
- Lesley was to co-star in the beautician comedy series Snip (1976), a TV takeoff of the Warren Beatty movie Shampoo (1975) starring David Brenner as a divorced hairdresser. Just before its scheduled September 30, 1976, debut, NBC abruptly canceled the show, so fast in fact that TV Guide did not even have time to remove a special feature on the show in its Fall Preview of September 18-24, 1976. Why? One of the show's supporting characters, a fellow hairdresser named "Michael", was openly gay and NBC got cold feet at the last minute. Had Snip (1976) premiered, it would have been a first on American series TV. Instead, Billy Crystal went on to receive that honor with his gay character a year later on the popular series Soap (1977). Seven episodes of Snip (1976) were completed when it got the ax. The only place the series ended up airing was in Australia, and it became the highest rated show in Australian history up until that time.
- She once enrolled in an acting class with drama coach Stella Adler.
- She's designated Elia Kazan's Splendor in the Grass (1961) as her favorite film.
- Was considered for the female lead in Finian's Rainbow (1968) that later went to Petula Clark.
- Was in a relationship with choreographer Jeffrey Hornaday (1977-1985).
- Lives in LA with husband Ron Taft, an ad executive.
- Is one of 26 actresses to have received an Academy Award nomination for their performance in a musical; hers being Victor/Victoria (1982). The others, in chronological order, are: Bessie Love (The Broadway Melody (1929)), Grace Moore (One Night of Love (1934)), Jean Hagen (Singin' in the Rain (1952)), Marjorie Rambeau (Torch Song (1953)), Dorothy Dandridge (Carmen Jones (1954)), Deborah Kerr (The King and I (1956)), Rita Moreno (West Side Story (1961)), Gladys Cooper (My Fair Lady (1964)), Julie Andrews (Mary Poppins (1964), The Sound of Music (1965), and Victor/Victoria (1982)), Debbie Reynolds (The Unsinkable Molly Brown (1964)), Peggy Wood (The Sound of Music (1965)), Carol Channing (Thoroughly Modern Millie (1967)), Kay Medford (Funny Girl (1968)), Barbra Streisand (Funny Girl (1968)), Liza Minnelli (Cabaret (1972)), Ronee Blakley (Nashville (1975)), Lily Tomlin (Nashville (1975)), Ann-Margret (Tommy (1975)), Amy Irving (Yentl (1983)), Nicole Kidman (Moulin Rouge! (2001)), Queen Latifah (Chicago (2002)), Catherine Zeta-Jones (Chicago (2002)), Renée Zellweger (Chicago (2002)), Jennifer Hudson (Dreamgirls (2006)), Penélope Cruz (Nine (2009)), Anne Hathaway (Les Misérables (2012)), and 'Meryl Streep (Into the Woods (2014)).
- Friend of Marianne Williamson.
- Sister of Richard Lewis Warren.
- Daughter of Margot Warren.
- Mother-in-law of Daniella Peters.
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