Jada Pinkett Smith, Christina Applegate, Mila Kunis, Kristen Bell, Kathryn Hahn, and Annie Mumolo in Bad Moms (2016)

Drew Barrymore, Christina Applegate, Charlie Day, Justin Long, and Jason Sudeikis in Going the Distance (2010)

Christina Applegate, Keith Coogan, Robert Hy Gorman, Danielle Harris, and Eda Reiss Merin in Don't Tell Mom the Babysitter's Dead (1991)

Christina Applegate in Samantha Who? (2007)

Christina Applegate, Rainn Wilson, Josh Gad, Emma Stone, and Teddy Geiger in The Rocker (2008)

Gwyneth Paltrow, Kelly Preston, and Christina Applegate in View from the Top (2003)

Jean Reno, Christina Applegate, and Christian Clavier in Just Visiting (2001)

Christina Applegate, Keith Coogan, Robert Hy Gorman, Danielle Harris, and Christopher Pettiet in Don't Tell Mom the Babysitter's Dead (1991)

Cameron Diaz, Christina Applegate, and Selma Blair in The Sweetest Thing (2002)

Christina Applegate in The Giving Tree (2000)

Christina Applegate and Richard Israel in Married... with Children (1987)

Milla Jovovich and Christina Applegate in Married... with Children (1987)

Christina Applegate and Linda Cardellini in We've Been Here Before (2022)

Christina Applegate and Linda Cardellini in Where Do We Go Now? (2022)

Christina Applegate in Saturday Night Live (1975)

Christina Applegate and Matt LeBlanc in Married... with Children (1987)

Christina Applegate, Will Ferrell, and Fred Willard in Anchorman: The Legend of Ron Burgundy (2004)

Christina Applegate in Married... with Children (1987)

Christina Applegate and Linda Cardellini in Dead to Me (2019)

Christina Applegate, Joe Don Baker, Lukas Haas, Jack Black, O-Lan Jones, and Sylvia Sidney in Mars Attacks! (1996)

Christina Applegate and Kevin Mangan in Mars Attacks! (1996)

Harrison Ford, Christina Applegate, and Will Ferrell in Anchorman 2: The Legend Continues (2013)

Christina Applegate in Web Therapy (2011)

Christina Applegate and Nina Dobrev in Crash Pad (2017)

Matt Dillon, Christina Applegate, and Steve Zahn in Employee of the Month (2004)

Christina Applegate, Will Ferrell, Steve Carell, David Koechner, and Paul Rudd in Anchorman: The Legend of Ron Burgundy (2004)

Christina Applegate in Suzanne's Diary for Nicholas (2005)