- Michelle Pfeiffer was already in the process of adopting a child by the time she met David. They had only been together for two months when their daughter Claudia Rose was added to their family.
- Has a son, John Henry, with his wife Michelle Pfeiffer. The son, born in 1994, is named after David's father.
- The most Kelley-created shows to be on at any given time was five during the 1999-2000 television season, with Chicago Hope (1994) on CBS, The Practice (1997) and Snoops (1999) on ABC, and Ally McBeal (1997) and Ally (1999) on Fox.
- Started writing as a hobby at the age of 27.
- Kelley became the first producer to win Emmy and Golden Globe Awards in both the Outstanding/Best Drama Series (The Practice (1997)) and Outstanding/Best Comedy Series (Ally McBeal (1997)) categories in the same year. [1999].
- David Kelley's father Jack Kelley was the former head coach for the Boston University Terriers hockey team and the first head coach for the New England Whalers of the World Hockey Association formed in 1972.
- Five of his series--The Practice (1997), Ally McBeal (1997), Boston Public (2000), Boston Legal (2004) and Harry's Law (2011)--are all part of the same universe.
- His father, Jack Kelley, was at one time director of operations for the Glens Falls [New York] Civic Center.
- Has an adopted daughter named Claudia Rose (born in 1993) with Michelle Pfeiffer.
- He became the second person ever to win Emmy Awards for producing across all three genres: Comedy, Drama & Limited Series/TV Movie since Brian Grazer.
- Brother-in-law of Dedee Pfeiffer and Lori Pfeiffer.
- Both of his parents died in 2020.
- Brother in-law of Kevin Ryan.
- Is of Irish and Scottish descent.
- Has 3 siblings.
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