Michael Douglas, Albert Brooks, Ryan Reynolds, and Maria Ricossa in The In-Laws (2003)

Ryan Reynolds and Hugh Jackman in Deadpool & Wolverine (2024)

Ryan Reynolds, Hugh Jackman, and Peggy the Dog in Deadpool & Wolverine (2024)

Ryan Reynolds and Leslie Uggams in Deadpool & Wolverine (2024)

Ryan Reynolds in Deadpool & Wolverine (2024)

Ryan Reynolds and Morena Baccarin in Deadpool & Wolverine (2024)

Ryan Reynolds, Randal Reeder, Leslie Uggams, Lewis Tan, and Rob Delaney in Deadpool & Wolverine (2024)

Ryan Reynolds and Rob Mac in Welcome to Wrexham (2022)

Ryan Reynolds and Morena Baccarin in Deadpool (2016)

Wesley Snipes, Jessica Biel, and Ryan Reynolds in Blade: Trinity (2004)

Tara Reid and Ryan Reynolds in Van Wilder (2002)

Ryan Reynolds and Melissa George in The Amityville Horror (2005)

David Paymer, Ryan Reynolds, Leila Johnson, Andrew Robb, and Shylo Sharity in School of Life (2005)

Ryan Reynolds, Dane Cook, Anna Faris, Justin Long, and Andy Milonakis in Waiting... (2005)

Ryan Reynolds and Amy Smart in Just Friends (2005)

Ryan Reynolds and Bonnie Root in Coming Soon (1999)

Jeremy Piven, Ryan Reynolds, and Alicia Keys in Smokin' Aces (2006)