- Gave birth to her second child at age 35, daughter Gloria on September 18, 2011. Child's father is her husband, Michel Hazanavicius.
- Her favorite movie is Laura (1944).
- Her parents agreed to call her Bérénice because his father loved the Edgar Allan Poe short story by the same name while her mother, being fond of astronomy, had in mind the Coma Berenice (Berenice's hair) constellation.
- Is the second Argentine-born actress to be nominated for an Oscar. The first was Norma Aleandro.
- Hobbies include biking, writing, photography and collecting 1920s hats.
- The only winner of the Best Actress César to be nominated for the Best Supporting Actress Oscar for the same performance.
- Daughter of director Miguel Bejo and Silvia De Paoli, a lawyer. She has three younger sisters. Her family is Argentinian, and has Spanish and Italian ancestry.
- Grew up in Paris, France.
- She studied karate with Alain Figlarz in preparation for her role in Koan (2002).
- Twice auditioned for a Bond girl role.
- Is one of 13 French actresses to have received an Academy Award nomination. The others in chronological order are: Claudette Colbert, Colette Marchand, Leslie Caron, Simone Signoret, Anouk Aimée, Isabelle Adjani, Marie-Christine Barrault, Catherine Deneuve, Juliette Binoche, Marion Cotillard, Emmanuelle Riva and Isabelle Huppert.
- Host of the 65th Cannes Film Festival.
- Gave birth to her first child at age 31, son Lucien on June 25, 2008. Child's father is her husband, Michel Hazanavicius.
- Was considered for the role of Rita in Edge of Tomorrow (2014), but Emily Blunt was cast instead.
- She's a big fan of Marilyn Monroe.
- Returned to work three months after giving birth to her daughter Gloria to begin filming Populaire (2012).
- A fan of The Sopranos (1999).
- Sister of Moira Grassi.
- Sister-in-law of Serge Hazanavicius.
- Supported Lionel Jospin's 2002 presidential campaign.
- Had agreed to star in Florent-Emilio Siri's "La bande à Bonnot", but the project was shelved when the distributor (Pathé) withdrew from it for budgetary reasons. The movie would have co-starred Matthias Schoenaerts as criminal anarchist Jules Bonnot.
- Michele Placido initially approached her for the leading female role in The Choice (2015).
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