- In a botched 1980 surgical procedure, Dr. Norman Scott, longtime physician for the New York Knicks (1978-2005), operated on Peggy's right knee instead of her injured left knee. After she noticed the mix-up in the recovery room, he had to wheel her back in and fix the other one. She sued him for malpractice and was awarded $460,000 in 1985.
- She had an encyclopedic mind and appeared in many TV quiz shows in the 1960s.
- Was one of Jack Paar's stable of comedy players during his run as host of The Tonight Show Starring Jack Paar (1957) from 1958 to 1962, a period in which she also appeared regularly as a panelist on numerous game shows.
- Won Broadway's 1957 Tony Award as Best Supporting or Featured Actress (Dramatic) for "Auntie Mame," a part that she recreated in an Oscar-nominated performance in the film version of the same name, Auntie Mame (1958).
- Upon her death, her remains were interred at Church of the Ascension Cemetery in Greenwich Village in New York City.
- She studied drama at HB Studio in Greenwich Village in New York City.
- Graduated from Cambridge High & Latin School with fellow classmate Dallas Burroughs (Orson Bean.) Her English teacher was named.Mr. Romeo.
- The daughter of Raymond James and Margaret Cass.
- Has a brother named Jerry.
- She was married twice but did not have any children.
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