- Son of actor Dom DeLuise and Carol Arthur.
- In Happy (1983), he appeared with his father Dom DeLuise, his mother Carol Arthur and his brother, Michael DeLuise.
- Older brother of David DeLuise and Michael DeLuise.
- Bears a strong resemblance to his father, actor/comedian Dom DeLuise. Peter even occasionally cast his father on shows he directs.
- Named the character Loder in the Stargate SG-1 (1997) episode, The First Ones (2000), after his soon-to-be wife Anne Marie DeLuise.
- A couple of years after he finished 21 Jump Street (1987) he wanted to be a full time director.
- Son, Jake Dominick DeLuise, born April 11, 2004
- Uncle of actress Riley DeLuise.
- Married to Anne Marie DeLuise. (June 2002)
- He is of Italian and Germany ancestry.
- Auditioned for the role of Biff Tannen in Back to the Future (1985).
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