- Brian Huskey performs regularly at the Upright Citizens Brigade Theatre in both New York and Los Angeles. He is part of the sketch and improv quartet Naked Babies along with John Ross Bowie, Rob Corddry and Seth Morris.
- He attended University of North Carolina at Greensboro, graduating with a degree in English and minor in photography.
- Played bass in the rock band Bicycle Face from February 28, 1988 to August 30, 1994 in Greensboro, North Carolina.
- Relocated to New York City in the 90s to attend photo school and work as a photographer's assistant.
- He attended Charlotte Country Day School for the entirety of grade school, graduating in 1987.
- Perfect casting. as central character, Reggie Something, in perhaps the funniest X File of all, S11 Ep4 'The Lost Art of Forehead Sweat'. He was a forgotten co-agent with Mulder and Scully due to the Mingle/Mangala effect. Perfect frantic character who was convinced they were erasing him from public consciousness, Dr. Thaddeus Q They. The last line of the episode as Reggie being carted off by a sanatorium ambulance delivered by Skinner: "Hey, where in the hell are they taking Reggie?".
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